Tuesday, December 10, 2019
Business Law for Caltex Oil v Dredge 1976 â⬠MyAssignmenthelp.com
Question: Discuss about the Business Law for Caltex Oil v Dredge 1976. Answer: Introduction Caltex Oil (Australia) Pty Ltd v The Dredge Willemstad (1976) HCA 65 is deemed as amongst the leading cases when it comes to defending party being made liable for breaching the duty of care, where a physical injury was not caused, instead, the plaintiff suffered economic loss and the property for which this matter was brought forward, was not even owed by the plaintiff (Latimer, 2012). However, such damages are awarded only where the plaintiffs are affected in a direct manner due to the defendants carelessness particularly where the property of the plaintiff is damaged. This was deemed as a major case in Australian history as due to this case, the exception regarding the recovery of pure economic loss was presented (Sappideen, 2009). Where the losses are foreseeable in a reasonable manner, as a result of the circumstances surrounding the case, and the duty of care is violated, resulting in financial loss to plaintiff, the defendant would be required to compensate the plaintiff for the pure economic loss suffered by them due to their negligent behaviour (Robertson and Tilbury, 2016). In the following segments, this case has been analysed, where the issues and arguments raised by the parties, the courts decision and the background of the case has been elucidated. Factual Background Caltex Oil (Australia) Pty Ltd, herein referred to as Caltex, along with Australian Oil Refining Pty Ltd, herein referred to as AOR were the two parties who had a processing agreement drawn between them as per which, the refined crude oil of AOR was to be delivered to the refinery of AOR and this refiner was situated on the southern shore of Botany Bay. Further, Caltex was supposed to carry out this delivery. Upon the completion of this process, the refined products had to be sent back to Caltexs oil terminal, and this was situated at the northern shore of the Botany Bay by using the pipeline which was owned by AOR and had been located under the Botany Bay. The oil which came from the pipeline had ownership of Caltex due to the terms covered in the undertaken agreement and it was deemed as the obligation of AOR for making certain that no damage or loss resulted from the oil which was passing from the pipelines; further, it was also obligated towards the loss or damages as a result of associated risks (John Wiley, 2017). Dredge Willemstad, herein referred to as Dredge was the defendant in this matter. While he was dredging a water channel in the Botany Bay on 26th Oct, 1971, the pipeline was damaged.the operators had clear knowledge when they were dredging the water channel that the pipeline was present at that spot. The pipeline was damaged due to the inadequate track plotter chart which was prepared by Decca Survey Australia Ltd., herein referred to as Decca. The inaccurate portrayal of dredging area in addition to the shortfall of the operators of dredge in properly identifying the fault in track plotter chart along with their shortfall in checking the position by using conventional means was deemed as the reasons for the pipeline being damaged (John, Wiley, 2017). A case against dredge operators and Decca was initiated by AOR and they sought damages in form of compensation for the products and the pipeline which were damaged. The dredge operators and Decca were made responsible by NSW Supreme Court and damages of $125,000 were awarded to AOR. Caltex also initiated case against dredge operators and Decca for recovering the compensation for costs which Caltex had to incur for arranging the alternative way of transportation of petroleum products till such time of pipeline being repaired, which was damaged due to their negligence. However, the NSW Supreme Court rejected these claims owing to the reason that Caltex did not own the property and due to the loss being purely economic in nature. And so, a claim in the High Court was made by Caltex (John Wiley, 2017). Issues and arguments raised by parties The defendant relied upon the verdict given by the NSW Supreme Court and stated that they did not owe a duty for the economic loss which was caused in this case. They also stated that the appeal of the plaintiff should be quashed. The plaintiff, on the other hand, stated that the NSW Supreme Court had erred in the judgement just because of the absence of ownership, and appealed for the decision to be overturned. In this regard, they highlighted that there had been a duty owed towards the plaintiff which was contravened and which caused loss to the plaintiff (Lambiris and Griffin, 2016). The emphasis was laid down on the term loss. The plaintiff suffered an economic loss due to the negligence of the defendant. An economic loss was also a loss, even when it is differentiated from personal injury. And by not considering economic loss, it would be unfair to the plaintiff (Stewart, 2013). The standard of professional care which was required on part of Decca while they were drawing up their plans was not upheld. The duty of care was failed as they did not check if this plan was accurate as per the standard conventional means. The duty of care cannot be denied and the knowledge of the person having such profession cannot be denied. There was presence of the three major requirements of negligence in this case, i.e. remoteness of losses, reasonable foreseeability and direct causation (Greene, 2013). There was a clear foreseeability in the losses as a prudent person would have deployed care when they knew that the area in which they were dredging had a pipeline situated below it (Bingham, 2011). The dredges did not take the reasonable care which resulted in a direct loss to the plaintiff. The damages were substantial in nature and could not be deemed as remote just because of their economic nature. The work of plaintiff was suffered gravely and they had to incur additional costs, for transportation, which would not be a requirement, had the duty of care been fulfilled. And so, the plaintiff requested for being compensated (Burrows, 2013). With regards to the point raised in the case from which this appeal was derived, particularly for damages not being awarded as the plaintiff was not the owner of the property, the case of Main v. Leask 1910 SC 772 had to be referred. In this case, the fishing boat sunk due to another vessels shortfall. This boat was working based on agreement in which the profits earned from the boat were required to be divided between the owner of the boat and the members of crew. Crew made a claim for compensation of profits due to the loss which they suffered from the sinking of ship. The Court of Session upheld this particular claim (Think, 2017). Applying the ruling given by Lord Ardwall in this case, to the case in discussion, the plaintiff argued that the damage was suffered due to fault of others and this permitted them to make a case of economic loss against the defendant. The crew was granted relied when they were not the boat owners and in this regard, the plaintiff was also to be paid the damages as per the arguments put forward by the plaintiff (Austlii, 2017). The Seaway Hotels Ltd. v. Cragg (Canada) Ltd. (1959) 21 DLR (2d) 264, which is a case of Ontario Court of Appeal was also highlighted in this case. This case revolved around the feeder line which carried electricity to hotel and broke down negligently. Due to this, the applicances of the hotel did not work in a proper manner and the food spoiled. Also, the dining room and the bar had to be shut down before the normal closing time. The hotelkeepers successfully sued for the loss of food and the economic loss caused due to closure of dining room and bar. The key point here was the loss being foreseeable and this led to the economic loss being considered as a physical loss (Jade, 2017). And so, the plaintiff requested the court that on the basis of foreseeability, owing to their awareness about the pipeline, the defendant should be made liable (Denton, 2017). Decision of Case In order to give their decision, the court considered the points raised by the plaintiff and the defendant. They also considered certain other points like the case of Morrison Steamship Co. Ltd. v. Greystoke Castle (Cargo Owners) (1947) AC 265. The statement given in this case provided the sphere of obligation of care based on negligence, to be dependent on the courts assessment in the demand of society for protecting from the carelessness of others. So, for economic protection, there was a need to consider the width and size of the potential claims. This case allows for the claims of the plaintiff to be upheld and to adequately protect the plaintiff for the economic losses (Jade, 2017). This case saw a unanimous decision being given by the judges and the plaintiffs claims being upheld by the High Court. The court accepted the points which were raised by the plaintiff, particularly based on the quoted case laws. As a result of this, the plaintiff was awarded damages for the pure economic loss which the plaintiff had to bear due to the defendant being negligent and failing in fulfilling their respective duties. The raison d'tre which led to the verdict being given was majorly due to the reasonable foreseeability of the loss, which was aptly highlighted by the plaintiff, to be present in this particular matter (Kidner, 2012). It was held by the court that the defendant held clear knowledge that there was a possibility of a loss resulting from their activity, which could be physical or economic, due to their work being undertaken in a careless manner and which was opposed to the required standard of care. Due to this reasonable foreseeability of the losses, there was a need for the defendant to be held responsible for their actions (Ward, 2010). All this led to the defendants owing a duty of care to Caltex and failing in apprehending the possibility of the loss to plaintiff in a reasonable manner owing to the breakage or damage to the pipes. And as a result of the duty of care being contravened by the defendant, the court upheld the appeal of the plaintiff (Coveney, 2007). The decision given in this case was quite right and the court had rightly emphasized over the economic losses being made payable when there was clear and reasonable foreseeability of the pipeline being damaged when the work of dredging was being undertaken. Also, a faulty map is bound to result in improper work and for not undertaking their work properly, the court was right in upholding the claims of the plaintiff and holding the defendant liable for the pure economic loss which the plaintiff had to bear, in terms of the additional costs of transportation for the period during which the pipeline had been damaged. Conclusion In the preceding parts, a thorough discussion took place with regards to the claims which were raised by Caltex against the dredges and Decca. The arguments of the parties, and the factual background were also highlighted in the previous parts to present a conclusive summary of this case. In this case, the High Court was appealed to by the plaintiff and they decided upon whether or not the plaintiff should be allowed to claim damages from the defendant for the pure economic loss, particularly when the plaintiff did not own the pipeline which was damaged and had been actually a third party in this case. However, the reasonable foreseeability led to the case being ruled in favour of the defendant, along with the case laws in the past where third parties were awarded damages for pure economic loss. This is a key case because a third party was awarded damages for pure economic loss as the requirements of negligence were fulfilled. References Austlii. (2017) Caltex Oil (Australia) Pty Ltd v Dredge "Willemstad" [1976] HCA 65; (1976) 136 CLR 529 (9 December 1976). [Online] Austlii. Available from: https://www.austlii.edu.au/cgi-bin/sinodisp/au/cases/cth/HCA/1976/65.html?stem=0synonyms=0query=Caltex%20Oil [Accessed on: 28/09/17] Bingham, T. (2011) Lives of the Law: Selected Essays and Speeches: 2000-2010. Oxford: Oxford University Press. Burrows, A. (2013) English Private Law. 3rd ed. Oxford: Oxford University Press. Coveney, G. (2007) Who Said You Cant Have It All? The Perils of Ignoring Risk Allocation in Cases of Relational Economic Loss. [Online] Bond University. Available from: https://epublications.bond.edu.au/cgi/viewcontent.cgi?article=1331context=blr [Accessed on: 28/09/17] Denton, D.H. (2017) Economic loss Principles In Brief. [Online] David H Denton. Available from: https://www.davidhdenton.com/uploads/2/3/1/2/23125402/economic_loss_-_principles_in_brief.pdf [Accessed on: 28/09/17] Greene, B. (2013) Course Notes: Tort Law. Oxon: Routledge. Jade. (2017) Caltex Oil (Australia) Pty Ltd v Dredge "Willemstad". [Online] Jade. Available from: https://jade.io/article/66636 [Accessed on: 28/09/17] John Wiley. (2017) Caltex Oil (Australia) Pty Ltd v The Dredge Willemstad. [Online] John Wiley. Available from: https://www.johnwiley.com.au/highered/carlon_accounting4e/content/case_summaries/ch04/CaltexOil_v_TheDredgeWillemstad.doc [Accessed on: 28/09/17] Kidner, R. (2012) Casebook on Torts. 12th ed. Oxford: Oxford University Press. Lambiris, M., and Griffin, L. (2016) First Principles of Business Law 2016. Sydney: CCH Latimer, P. (2012) Australian Business Law 2012. 31st ed. Sydney, NSW: CCH Australia Limited. Robertson, A., and Tilbury, M. (2016) Divergences in Private Law. Oxford: Hart Publishing. Sappideen, C., at al. (2009) Torts, Commentary and Materials. 10th ed. Pyrmont: Lawbook Co, pp. 309-311. Stewart, M.A. (2013) Law, Morality and Rights. New York: Springer. Think. (2017) Caltex Oil (Australia) Pty Ltd v Dredge "Willemstad" [1976] HCA 65; (1976) 136 CLR 529 (9 December 1976). [Online] Think. Available from: https://think.io/pub/Law%20Notes/Torts/CALTEX%20OIL.txt [Accessed on: 28/09/17] Ward, P. (2010) Tort Law in Ireland. The Netherlands: Kluwer Law International.
Tuesday, December 3, 2019
The Importance of Theory Sample Essay Example For Students
The Importance of Theory Sample Essay Bennerââ¬â¢s theory of Novice to Expert has been adopted by the operating room where I pattern. This theory was chosen because the operating room has alone educational demands and novice versus adept hierarchy issues that are non normally found in general nursing units. The purpose of this paper is to give a brief history of the development of nursing and how the pattern of nursing has evolved into a theory based profession. The following subdivision. Bennerââ¬â¢s theory. Novice to Expert. will incorporate an analysis of the cardinal constructs of the theory and how this theory relates to the nursing metaparadigm. The 3rd subdivision will exemplify how Bennerââ¬â¢s theory is applied in clinical pattern and sketch the functions of nurses. nursing leading and nurse pedagogues. Last. the 4th subdivision will reason what has been learned from analysing this theory. We will write a custom essay on The Importance of Theory Sample specifically for you for only $16.38 $13.9/page Order now The Importance of Nursing Theory The nursing profession has been around for centuries. long before formal instruction was introduced. In 1863 the University of Pennsylvania offered a six month class in nursing. and is considered one of the first organized schools for nurse in the United States. Many other schools followed suit. and began offering formal instruction for nurses under the way of doctors. and was structured as an on-the-job preparation plan within the infirmaries. These colleges taught the same theoretical format to the nursing pupils. utilizing chiefly regulations. rules of pattern and traditions. In the same epoch. Florence Nightingale was making an instruction and theoretical attack to nursing in Europe. As the profession established itself as a care-maiden to doctors. the profession and the theory of nursing pattern didnââ¬â¢t progress until about a century subsequently. Get downing in the early 1950s. nursing pattern took a dramatic alteration from regulations and tradition to scientifically based higher instruction and pattern theory. In the seventies. the National League of Nursing required that nursing course of study be based on theoretical and conceptual model. At this clip theorists began to progress and spread out as colleges taught nursing theory as a model for higher instruction. Nursing theory defines the nature. construction. constructs and relationships between nursing constructs ( Fawcett 1995. Meleis 2005 ) . Patricia Benner is a nursing theoretician who foremost published From Novice to Expert: Excellence and Power in Clinical Nursing Practice. in 1984. This theory is still widely used and respected. and has continued to germinate. Harmonizing to Benner. the theory of nursing encompasses both the medical and nursing scientific cognition that has been imparted to the trainee. largely in nursing school. and the regulations of pollex tha t are mostly acquired during on-the-job preparation and experience ( Benner. Tanner A ; Chesla. 2009 ) . This theory outlines the development of the nurse from novitiate to expert in professional pattern and focuses on the nurseââ¬â¢s function independent of the doctor. Bennerââ¬â¢s Theory. Novice to Expert Bennerââ¬Ës theory. Novice to Expert. provinces that pattern and theory are intertwined. Neither can stand entirely. and each drama an built-in function in the development and proficiency of the practicing nurse. To farther depict the importance of the relationship between theory and pattern and specify the intent of the theory. Benner provinces. ââ¬Å"nursing is a lovingness pattern that goes beyond theory wholly and shows that where human significance is at interest. one needs a sort of intuition that can neer be captured by rational theory. theory is dependent on pattern. and ground requires intuitionâ⬠( Benner. Tanner A ; Chesla. 2009 ) . This has been my experience as a new nurse in the operating room many old ages ago and. soon. as an operating room nursing manager. Bennerââ¬â¢s theory is designed around several stages in the development of the nurse from come ining the field after graduation. to accomplishing a degree of pattern competency. to going an expert wit h the ability to present sound. consistent clinical judgement. .u37e04f288b33177711418efde7e7e47b , .u37e04f288b33177711418efde7e7e47b .postImageUrl , .u37e04f288b33177711418efde7e7e47b .centered-text-area { min-height: 80px; position: relative; } .u37e04f288b33177711418efde7e7e47b , .u37e04f288b33177711418efde7e7e47b:hover , .u37e04f288b33177711418efde7e7e47b:visited , .u37e04f288b33177711418efde7e7e47b:active { border:0!important; } .u37e04f288b33177711418efde7e7e47b .clearfix:after { content: ""; display: table; clear: both; } .u37e04f288b33177711418efde7e7e47b { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u37e04f288b33177711418efde7e7e47b:active , .u37e04f288b33177711418efde7e7e47b:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u37e04f288b33177711418efde7e7e47b .centered-text-area { width: 100%; position: relative ; } .u37e04f288b33177711418efde7e7e47b .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u37e04f288b33177711418efde7e7e47b .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u37e04f288b33177711418efde7e7e47b .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u37e04f288b33177711418efde7e7e47b:hover .ctaButton { background-color: #34495E!important; } .u37e04f288b33177711418efde7e7e47b .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u37e04f288b33177711418efde7e7e47b .u37e04f288b33177711418efde7e7e47b-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u37e04f288b33177711418efde7e7e47b:after { content: ""; display: block; clear: both; } READ: How to Write a Profile EssayThe nursing metaparadigm outlines nursing attention in four basic constructs. individual. environment. wellness and nursing pattern. The inquiry is. are new nurses able to run into the four constructs of the nursing metaparadigm upon entry into pattern? Bennerââ¬â¢s premiss was centered on an country of nursing that had non been studied. the existent pattern and clinical acquisition of new nurses ( Benner. 1984. Benner. A ; Benner. 1979 ) . In 2001. the National Council of State Board of Nursing was describing something really similar. ââ¬Å"new nurses enter pattern feeling unprepared. and they report that employers rank the readying for ne w registered nurses as inadequate in many areasâ⬠( National Council of State Boards of Nursing ( NCSBN. 2001 ) . Bennerââ¬â¢s theory designs a civilization of recognition that Fosters learning and larning through the continuum of the nurseââ¬â¢s calling. This is in an attempt to supply safe. competent attention to every patient. every clip. When the theory is followed. the nurse can guarantee the demands of the patient within the nursing metaparadigm are reached. Novice to Expert in Clinical Practice Bennerââ¬â¢s Novice to Expert theory places the burden on nursing leading and pedagogues to plan orientation processes to help the new nurse in the passage from school to pattern. One such recommendation provinces. ââ¬Å"a new-graduate residence plan lasting at least 1 twelvemonth with planned coursework. mentoring. and usage of first-person experience-near-nursing narrations of experiential acquisition to assist new nurses reflect on their experiential acquisition and joint what they are larning in practiceâ⬠( Geertz. 1987 ) . This closely theoretical accounts the Association of Operating Room Peri-operative Nurse 101 developing plan that is in topographic point in the establishment where I pattern. Every nine months two nurses are selected ( either new alumnus or experienced ) and are put through an integrated didactic and practical preparation plan. They are given lessons on pattern theory so paired with a don for on-the-job preparation. Regular ratings are performed and the nurse bit by bit evolves into unsupervised pattern. The novitiate nurses in this plan become safe. confident. competent nurses who are able to acknowledge when they are non the best qualified individual to run into the demands of the patient. On the opposite terminal of Bennerââ¬â¢s theory is the adept nurse. The expert nurse has frequently been an unclear participant in the attention of the patient. This nurse is the ââ¬Å"go-toâ⬠individual that solves alone jobs or has experience with alone clinical presentation. In an article turn toing patient mortality rates. the writers Aikinm. Smith and Lake suggest the nurse expert should be treated as: ââ¬Å"While competent clinical nurses are extremely skilled. the ability of the adept nurse to be proactive instead than reactive. and to see and move on behalf of the patient before the formal indexs are clear. is such a spring in applied nursing that their public presentation must be recognized. rewarded. and provided the organisational support to run effectivelyâ⬠( Aikin. Smith. A ; Lake. 1994 ) . In the operating room where I pattern. nurse experts are acknowledged as experts and have a duty that comes with that differentiation. Meeting the demands of the pati ent does non ever intend merely patient attention. The adept nurse is able to lend to the nursing metaparadigm constructs of individual. environment. wellness and nursing pattern in a more extremely skilled manner. Some adept nurses are trained as dons and work in the peri-op preparation plan to assist novitiate nurses grow and view the patient as a complex being. and acquire beyond executing merely undertakings. Many adept nurses take part in shared-leadership undertakings such as patient safety. operating room efficiencies and patient satisfaction. These functions address infirmary policy and aid set procedures in topographic point that make the multifaceted attention of the patient safer and more efficient. In an attempt to besides take the expert into their following functions as leaders. expert nurses are put into the hospitalââ¬â¢s endowment mapping plan for future publicities and leading preparation. Bringing nursing theory to the head of our mundane pattern has had a positive consequence on the nurses. phsycians and patien ts. No longer do we believe a nurse is a nurse. There is a witting recognition of the skill sets of practicians and everyone is proud of their functions in the patient experience. Decision .uac2e8f28ec2bd1714a47fcb24111dc41 , .uac2e8f28ec2bd1714a47fcb24111dc41 .postImageUrl , .uac2e8f28ec2bd1714a47fcb24111dc41 .centered-text-area { min-height: 80px; position: relative; } .uac2e8f28ec2bd1714a47fcb24111dc41 , .uac2e8f28ec2bd1714a47fcb24111dc41:hover , .uac2e8f28ec2bd1714a47fcb24111dc41:visited , .uac2e8f28ec2bd1714a47fcb24111dc41:active { border:0!important; } .uac2e8f28ec2bd1714a47fcb24111dc41 .clearfix:after { content: ""; display: table; clear: both; } .uac2e8f28ec2bd1714a47fcb24111dc41 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .uac2e8f28ec2bd1714a47fcb24111dc41:active , .uac2e8f28ec2bd1714a47fcb24111dc41:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .uac2e8f28ec2bd1714a47fcb24111dc41 .centered-text-area { width: 100%; position: relative ; } .uac2e8f28ec2bd1714a47fcb24111dc41 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .uac2e8f28ec2bd1714a47fcb24111dc41 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .uac2e8f28ec2bd1714a47fcb24111dc41 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .uac2e8f28ec2bd1714a47fcb24111dc41:hover .ctaButton { background-color: #34495E!important; } .uac2e8f28ec2bd1714a47fcb24111dc41 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .uac2e8f28ec2bd1714a47fcb24111dc41 .uac2e8f28ec2bd1714a47fcb24111dc41-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .uac2e8f28ec2bd1714a47fcb24111dc41:after { content: ""; display: block; clear: both; } READ: What Leads to Intervention?: A Case Study of Inter EssayNursing pattern is an of all time altering field. Theories in nursing have evolved. and much like Bennerââ¬â¢s theory. the theory takes on deeper penetration into the attention of the patient with regard to the development of nurses pattern accomplishments and experience and is relevant in todays pattern. Bennerââ¬â¢s theory is designed to steer nurses and nurse leaders in the ripening procedure of nursing accomplishments and to promote those accomplishments to the following degree. Nurses must continuously intermix practical experience and established theory to make a safe. holistic experience for every patient . every clip. Aiken. L. H. . Smith. H. L. . A ; Lake. E. T. ( 1994 ) . Lower Medicare mortality among a set of infirmaries known for good nursing attention. Medical Care. 32. 771ââ¬â787. Benner. P. E. . Tanner. C. A. . A ; Chesla. C. A. ( 2009 ) . Expertness in Nursing Practice: Lovingness. Clinical Judgment A ; Ethical motives. New York: Springer. Benner. P. A ; Benner. R. V. ( 1979 ) . The new nurseââ¬â¢s work entry: A troubled sponsorship. New York: Tiresias. Fawcett J. ( 1995 ) Analysis and Evaluation of Nursing Theories. Philadelphia: Davis. Geertz. C. ( 1987 ) . Interpretative societal scientific discipline: A 2nd expression ( pp. 195ââ¬â240 ) . Berkeley: University of California Press. Kaariainen. M. . Kanste. O. . Elo. S. . Polkki. T. . Miettunen. J. . A ; Kyngas. H. ( 2011 ) . Testing and verifying nursing theory by collateral factor analysis. Journal of Advanced Nursing. 67 ( 5 ) . 1163-1172. doi:10. 1111/j. 1365-2648. 2010. 05561. ten Meleis A. I. ( 2005 ) Theoretical Nursing: Development A ; Progress. Philadelphia: J. B. Lippincott Company. National Council of State Boards of Nursing. ( 2002 ) . Report of findings from the 2001 Employers Survey ( Research Brief. Vol. 3 ) . Chicago.
Wednesday, November 27, 2019
Using Conflicts in Decision Making to Make Effective Decisions and a More Cohesive Group Essay Example
Using Conflicts in Decision Making to Make Effective Decisions and a More Cohesive Group Essay Using Conflicts in Decision Making to Make Effective Decisions and a More Cohesive Group Conflicts arise between co-workers often and over many different matters. Mismanaged conflicts can damage relationships and stalemate group decisions. By learning conflict resolution skills, workers can seize opportunities for growth and open discussion. One can use conflicts that arise in group decision making to make more effective group decisions and a more cohesive group. Conflicts in Group Decision Making Tubbs (2007, p. 09), defined conflict management as The ability to manage conflict so that there is a healthy conflict of ideas without the unhealthy conflict of feelings. Conflict is often thought of as a completely negative event, when in fact it can have many positive effects. Without some form of conflict, problems would not ever be revealed or dealt with. Although there are many cost associated with conflict, there are also many benefits that are often overlooked. Personal Conflicts P ersonal conflict arises out of a sense of being wronged. The perception of inequality, scarcity, and moral or cultural differences gives rise to a emotional grievance (Brahm, 2004, para. 1). Acting out these conflicts is a way of addressing concerns. conflict can give rise to new norms and rules to govern conduct which can have long-term benefits conflict can lead to establishing new statutes meant to deal with the sources of conflict (Brahm, 2004, para. 8). Idea Conflicts Idea conflicts are a difference of opinion. People can have idea conflicts and have no personal conflict- as long as they respect other peoples point of view. Idea conflicts are necessary to create idea diversity. A homogenous set of ideas will not be as creative, comprehensive, or open to new ideas. Ideas conflict can also easily escalate into personal conflicts when workers become more loyal to an idea than to the group synergy. Make Effective Group Decisions With Conflict Building Collaborative Solutions, Inc. (BCS), defines conflict management as the opportunity to improve situations and strengthen relationships' (Tubbs, 2007, p. 315). By resolving disagreements before they turn into personal conflict, workers can keep their focus. We will write a custom essay sample on Using Conflicts in Decision Making to Make Effective Decisions and a More Cohesive Group specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Using Conflicts in Decision Making to Make Effective Decisions and a More Cohesive Group specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Using Conflicts in Decision Making to Make Effective Decisions and a More Cohesive Group specifically for you FOR ONLY $16.38 $13.9/page Hire Writer Conflicts are often easier to handle when put into proper perspective (Sherman, 2011, p. 52). An open exchange of ideas can contribute to organizational health by valuing honorable conflicts of ideas. Group member should expect and respect differing points of view, while maintaining personal sovereignty of thought. Conflict Solutions conflict can initiate a process through which individuals realize they have common interests and common enemies (Brahm, 2004, para. 10). New bonds can be made in conflict, even as others are being broken down. Outside conflict can bond and energize group members (Tubbs, 2007, p. 315). The challenge is to realize the benefits of conflict in such a way so as to minimize the many costs also associated with conflict (Brahm, 2004, para. 14). If a company provides conflict resolution training to employees, they can reduce the intensity and frequency of future conflicts. Groupthink The term groupthink was coined in the 1970s to describe a situation when a group makes faulty decisions because group pressures lead to a deterioration of mental efficiency, reality testing and moral judgment within a board (Martyn, 2011, para. ). Groupthink can be effectively be mitigated by a healthy expression of the conflict of ideas. Members of a group guilty of groupthink are usually more concerned with group harmony than with effective decision making (Martyn, 2011, para. 3). When attention is drawn to the hazards of groupthink and benefits of idea diversification, then the group can focus on the best interest o f the organization. Cohesion When conflict resolution happens out of empowerment and collaboration, it allows for more growth and more positive opportunities to be presented. When personal growth is shared between team members it produces bonds learn positive ways of addressing conflict that will minimize hurt feelings, gossip, and a negative environment. Leaders should recognize that organizational level decisions can have an immense effect on both functional and dysfunctional conflict (Harris, Ogbonna, Goode, 2008, p. 453). Perspective be open to the other persons perceptions-instead of casting blame, explore how you both may have contributed to the situation (Freinkel,2004, para. ). Bringing the causes of conflict to the surface will allow for the root problem to be dealt with. No matter who youre dealing with, asking open-ended questions is a great way to create a dialogue (McCurdy, n. d. , p. 3). Discovering the best level of analysis requires a certain navigational skill, a nimble capacity to zoom in, out, and around to different perspectives (Sherman, 2011, p. 52). Conclusion A certain amount of conflict is inevitable, and it must be understood to be channeled. Conflict can be used as an opportunity to grow and improve group interaction. Conflict and resolution is not a zero-sum game; there are benefits when one looks for them. Group cohesion and decision making can certainly be enhanced through the conflict and resolution process. References Brahm, E. (2004). Benefits of Intractable Conflict. Retrieved April 26, 2011 from http://www. beyondintractability. org/essay/benefits/ Freinkel, S. (2004, July/August). can we talk? Health, 18(6), 135-138. Harris, L. C. , Ogbonna, E. , Goode M. H. (2008). Intra-functional conflict: an investigation of antecedent factors in marketing functions. European Journal of Marketing, 42(3/4), 453-476. doi:10. 1108/03090560810853011 Martyn, K. (2011, March). Governance groupthink. New Zealand Management, 58(2), 55-56. McCurdy, S. (n. d. ). 5 ways to resolve conflict at work. Retrieved April 24, 2011 from http://www. click2houston. com/money/24926751/detail. html Sherman, J. (2011, March/April). Zoom. Psychology Today, 52-53. Tubbs, S. L. , (2007). A Systems Approach to Small Group Interaction (9th ed. ). Ney York, NY: McGraw Hill.
Saturday, November 23, 2019
Pharmaceutical Industry in India Essays
Pharmaceutical Industry in India Essays Pharmaceutical Industry in India Essay Pharmaceutical Industry in India Essay Industry overview Pharmaceutical sector is an important industry of any modern day economic power. Pharmaceutical industry in India has a very humble past. After independence, development of pharmaceutical industry was one of the top agenda of government along with steel and manufacturing industry. The market was protected against competition for a long period of time by giving incentives to small firms, license-raj etc. Today the Indian pharmaceutical industry is the front-runner science-based industries in the country. Today the industry boasts of wide ranging capabilities in the complex field of drug manufacture and technology. The sector is pegged to be worth US$ 7. 3 billion. The annual growth rate is estimated to be around 13%. Reports suggest that the domestic retail market would be worth around US$ 12 billion by 2012. Indian pharmaceutical industry ranks 4th in terms of volume globally and 13th in terms of value. It has 8% share in global sales 20%-24% share in production of generic drugs. The domestic players satisfy almost all of the countryââ¬â¢s demand for formulations and bulk drugs. Indian firms arenââ¬â¢t limited to domestic market; they are now competing head on with multi national players in international arena. For many firms, exports constitute 60%-70% of the total revenue earned. Reasons for this strong growth are low cost of manufacturing, low cost of RD, innovative scientific manpower etc. The total pharmaceutical exports in 2007-08 clocked US$ 6. 68 billion against US$ 5. 73 billion in 2006-07 recording a growth rate of 16 per cent. India is poised to be one of the fastest growing pharmaceutical markets in the world. This has led to entry of many major companies in the Indian market and a huge amount of FDI inflow. Evolution of the Indian Pharmaceutical Industry The Indian regulatory system made several arrangements to protect the domestic pharmaceutical industry from foreign competition in its nascent phase. One of them was recognition of only process patents. This built a sound and strong base for strong and competitive domestic market but deterred entry of foreign players. The life of Indian pharmaceutical industry can be broadly divided into two phases, namely Pre-Patent regime and Post-Patent regime respectively. Lets take a look at both of them in detail: Pre-Patent Regime: This period can be segmented into various time periods for better understanding: 1947-1970 During this period country was trying to stand on its feet after gaining independence. The pharmaceutical industry had to be built from scratch. Though several domestic players had sprung up in market but their impact on market was limited. The reason was their inability to compete with MNC players who had better access to resources, better technical know how and access to larger amount of funds. These foreign players imported formulations and sold them in India. They were neither contributing to pharmaceutical industries nor to the manufacturing industries in India. People had low spending and restricted access to healthcare facilities because of low levels of income. The government had realized that dependence on imported drugs had to be reduced so that essential drugs could be made available to public at cheap prices. For this country needed to build indigenous drug production capabilities. To fulfill this objective Hindustan Antibiotics Limited (HAL) and Indian Drugs Pharmaceutical Limited (IDPL) were setup in 1954 and 1961 respectively. These companies soon established themselves as major producers of critical drugs, which, were being imported at that time. 1970-1979 The MNCs continued to dominate the domestic market in spite of steps taken by government. Government introduced two legislations in 1970 to accelerate the process of self-reliance and indigenization. These were Indian Patent Act and Drug Price Control Order (DPCO). These two regulations provided the launch pad for the Indian pharmaceutical industry to take off into a new growth spiral. Indian Patent Act: The act granted patents only for methods and processes used to manufacture the substance. This allowed the domestic players to reverse engineer the drugs present in market and find its constituents. They started making the product using the same bulk drug by using a modified production process. Drug Price Control Order: Government regulated prices of 354 essential bulk drugs and formulations to ensure wide spread availability of drugs at a reasonable price. These two legislations changed the industry structure and growth pattern. Several small-scale ndustries (SSI) came into existence in formulation business. They had significant advantage as their products were out of purview of price control. Low entry barriers, abundance of bulk drugs and dispersed market acted as additional catalysts. All these factors had a significant impact on the position of MNCs in India. These regulations introduced the concept of price control did not recognize product patents. Therefor e the MNCs had no incentive of introducing new drugs in the market. Their overall share in formulations started to decline as time progressed. 1979-1987 Government in 1979 amended DPCO. Number of drugs under purview of DPCO was bought down from 354 to 163. Government also increased the permissible mark-up on drugs from 40%-60% to 75%-100%. DPCO also regulated the production by fixing ratio between formulation and key bulk drugs. This ensured continuous and uninterrupted supply of key bulk drugs. Investments made by government in past had started bearing fruit. IDPL and HAL provided technical assistance to smaller players in establishing their foothold. Hence even smaller players started to supply critical drugs to market. Indian firms started to invest in RD because of availability of skilled researchers in country. This resulted in launch of new drugs through process re-engineering. Government funded Central Drug Research Institute (CDRI) and Council of Scientific and Industrial Research (CSIR) made major contribution to the research base. Indian firms had advantage of low cost structure and very good reverse engineering technical skills. After they had established themselves in domestic market they turned their attention towards export. They took measures to utilize their advantage in global arena and were quite successful. There was no improvement in conditions of MNCââ¬â¢s. High tariffs caused the prices of their product to go up. Price control measures taken by government directed them to sell at cheaper price. Therefore they focused on specific sectors where they still had a stronghold. They were reluctant to launch new products in country because of lack of proper patent protection. This resulted in overall decline of their market share. 1987-1994 This was a consolidation period of the industry. The entire industry registered a double-digit growth rate through the period. This high growth rate was attributed to rise in per-capita income of people and introduction of new drugs at cheap price. The increase wasnââ¬â¢t limited to domestic market. While bulk drug production grew at CAGR of 16%, bulk drug export grew at CAGR of 40%. By 1994 exports comprised 50% of total bulk drug production. To meet the ever-increasing demand, companies had to invest heavily in increasing their capacities. High growth rate also attracted new players to the market. Competition in market increased manifold as the number of players in the market doubled over this period. Most important development of this period was liberalization program initiated by the government. The tariff barriers were lowered which leveled the playing field for MNCs vis-a-vis domestic players. This also increased foreign investment in domestic pharmaceutical industry. The liberalization policy also benefited domestic players who made efforts to increase their global presence due to lower tariff and non-tariff barriers. 1995-2001 The major development of this phase was governmentââ¬â¢s commitment to recognize product patent regime after 2005. This increased the expectation of MNCs. Most of them increased their equity stakes in Indian operations. MNCs also realized that they could convert India into their manufacturing base. India had quality manufacturing facilities at cheap costs. Domestic firms too had saturated Indian market. They were focusing on global markets more seriously now. They entered into alliances with MNCs, entered into JVââ¬â¢s in overseas market, set up world-class manufacturing facilities and strengthened their brands to strengthen their position. The small players finally came of age and gave serious competition to their bigger counterparts. Even though market grew at 15% intense competition from smaller players pushed the bigger players towards generic formulations. Bulk drugs had lower margins because of intense competition. To overcome this most players forward-integrated into formulation manufacturing or increased their export to non-regulated markets where margins were higher. 2001-2004 During this period domestic players increased their focus on market of generic drugs. They invested in RD and upgraded their manufacturing facilities to comply with GMP norms. During this period the domestic formulations market registered a decline, barring a few segments. MNCs were strengthening their interest in domestic market as product patent regime was to be implemented in 2005. Post-Patent Regime 2005-2006 Government passed an ordinance in 2005 implementing the product-patent regime. This move was aimed at bringing India at par with global pharmaceutical market. Other major developments during this period were implementation of VAT, shift in excise duty levy to MRP based levy and implementation of good manufacturing processes. During this period Indian players established themselves in global market with their innovatively engineered generic drugs API. 2006-2007 The new pharmaceutical policy has been center of attraction. Government wanted to bring essential drugs on which the manufacturers made fat profits under the purview of DPCO. The proposed pharmaceutical policy was aimed at bringing 354 essential drugs under purview of DPCO so that they are within reach of common man. The policy has provision of limiting MAPE to 150% to put a cap on profits earned by pharmaceutical firms. The duties on API were reduced to encourage manufacturing. Government has also set up NPPA to regulate pricing of drugs in India. Companies will have to sell their drugs at price decided by NPPA. Regulatory Environments in various parts of the world Europe The European Medicines Agency (EMEA) is the apex body, which governs medicine industry in Europe. Scientific opinions of the agency are prepared by committees i. e. the committee for medicinal products for human use (CHMP), the committee for medicinal products for veterinary use (CVMP), the committee for orphan medicinal products for rare diseases (COMP) and the new committee on herbal medicinal products (HMPC). EMEA performs the scientific evaluation of the quality, safety and efficacy of medicinal products in EU. EMEA also coordinates the resources for scientific evaluation and assessment regarding products undergoing the mutual recognition procedure and the master files for plasma and vaccine antigens. EMEA also provides guidance for companies requesting scientific advice. It also provides scientific advice before the application of new marketing authorization for centralized and mutual recognition procedures. Scientific Advice Working Party (SAWP) does this task. In order to sell products in EU markets firm have to obtain a license. This license is granted by CHMP after it assesses the product in question. European Pharmacopoeia (Ph Eur) specifies the quality specifications for pharmaceutical preparations and their ingredients. Before submitting a Marketing Authorization Application (MAA) the firm is required to show the safety and efficacy of the medicinal product. To show this local clinical data should be generated for a new medicinal product. Thus it is necessary to conduct clinical trails before launching a product in EU. If the product has already proved safety and efficacy in some other country then a bridging clinical study is sufficient. The initial license granted to a firm has to be renewed after five years. The risk-benefit balance is revaluated. If the result of re-evaluation is positive then the firm is granted the license for unlimited period of time unless the competent authority decides otherwise. In cases of drugs that require long-term safety study, the license for unlimited period is usually granted after 2-3 re-evaluations. The EU pharmaceutical legislation is very extensive and robust. In order to ensure high quality and safe therapies it provides extensive rules and guidance on licensing procedures for medicinal products. USA Pharmaceutical sector in USA is regulated by the department of Health and Human Services. The apex regulatory body is US FDA, which enforces the basic drug and food legislations. When a drug manufacturer develops a new drug, first the drug is tested on animals. Then he obtains approval for human trials through Investigational New Drug (IND). The data collected through human clinical trials in IND and animal studies is used to file a New Drug Application (NDA). NDA is used to communicate to FDA about safety and effectiveness of the drug, high quality manufacturing standard for the drug and appropriate labeling of the drug. New drugs are developed under patent protection. This grants exclusive marketing rights to the developer of the drug. After expiry of the patent period, other firms can sell a copy of the drug. This copied version of drug is called as generic drug. In order to get approval from FDA to sell generic drugs, firms must file for an Abbreviated New Drug Application (ANDA). Generic drug sector became very lucrative because the manufacturers of generic drugs didnââ¬â¢t have to invest in costly animal studies and human clinical trials. Also the pharmacists were given the right to sell substitute generic drugs instead of a specific drug unless explicitly specified by the doctor. To get an FDA approval for their ANDA the firms had to ensure that their drugs contains the same amount of active ingredient as the original drug, it should be identical in dosage form, strength and administration method and manufactured under the same manufacturing standards as for the original drug. A Drug Master File (DMF) is submitted to FDA that contains almost all information related o the drug. Some information in the file may be of confidential nature. India In India both the central government and the state government share the responsibility of regulating the pharmaceutical industry. The Drug and Cosmetic Act and Drug and Cosmetic Rule are the legislations passed by the government in this regard. Through this legislation the government regulates import, manufacture, sale and distribution of drugs in India. The central government plays as the coordinator of policies like drug approval, clinical trials, setting up standards, controlling the quality of imported drugs etc where as the state governments see that the policies laid down by the central government are being implemented by the firms. The Drug Controller General of India (DCGI) co-ordinates all the activities involved. Pharmaceutical industry in India regulated on basis of price, patent quality. DPCO fixes an upper limit on critical formulations API. NPPA regulates the pricing of all the drugs manufactured or sold in India. A firm cannot price its drug on its own; it has to be approved by NPPA. NPPA has also put an upper limit of 150% on MAPE. If the firm invests heavily in RD then the limit is increased by 50%. In 1995 government had amended DPCO to limit the size of drugs under purview of DPCO to 74. After implementation of product patent regime government is mulling over bringing the number of drugs under DPCO to around 200. The Drug Cosmetic act specifies the quality standards to be met for any drugs that is manufactured, sold or distributed in India. Manufactures have to follow GMP in their manufacturing plants. FDI up to 74% is allowed on the automatic route in the case of bulk drugs, their intermediate Pharmaceuticals and formulations (except those produced by the use of recombinant DNA technology). The Government considers FDI above 74% for manufacture of bulk drugs on a case-by-case basis. Itââ¬â¢s allowed only for manufacture of bulk drugs from basic stages and their intermediates. It also extends to bulk drugs produced by the use of recombinant DNA technology and the specific cell/tissue targeted formulations if it includes manufacturing from basic stage. Government had liberalization plans of increasing the FDI cap to 100% and making the process of investing more easily and investor friendly. The plans were not implemented because of political pressure exerted by the Left Parties on the government. Recent Developments Raw material shortage hits pharmaceutical firms Olympic games in China have put brakes on high-flying Indian pharmaceutical industry. In order to present its clean image before the world during the games, China has ordered to close various drug manufacturing units to prevent environmental degradation. This has caused a scarcity of raw material in India and has pushed up prices of generic medicines. Daiichi Sankyo buys majority stake in Ranbaxy Daiichi Sankyo Company, Ltd (Daiichi Sankyo) has bought majority stake in Ranbaxy Laboratories Limited (Ranbaxy) from the Singh family, the largest controlling shareholders of Ranbaxy. The deal is subject to regulatory approvals. This deal will allow Ranbaxy access to global markets that have been off-radar for the firm till now. Daiichi Sankyo is looking forward to gain a stronger foothold in a very fast developing Indian market as well as the base established by Ranbaxy in USA. Sun Pharmaceuticals gets USFDA nod for generic Depakote The USFDA has granted a final approval to Sun Pharmaceutical Industries Ltd for its Abbreviated New Drug Application (ANDA) for generic Depakote, divalproex sodium delayed release tablets. Divalproex sodium delayed release tablets are indicated as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures. US Congress to probe FDA`s Ranbaxy case The US House Energy Commerce committee is investigating the FDAs stance on the Ranbaxy case. The committee is to probe FDAs handling on Ranbaxys imports. The committee will also probe whether FDA knowingly let unsafe medicine to enter US. Sun Pharmaceuticals Taro deal Sun Pharmaceuticals, offered $454 million, all in cash, to buy out an Israeli generics manufacturer, Taro Pharmaceuticals. The deal has not been completed as yet because of encountering several roadblocks. Taro Pharmaceuticals is an Israeli pharmaceutical firm with a global presence. By acquiring Taro, Sun is trying to enter the low-competition, specialized segments like dermatology and pediatrics. Taroââ¬â¢s large presence in the Canadian market is also an attraction for Sun. Key Features of quarter April-June FY09 Improvement in product and geographic mix: Higher contribution from exports (62%) for generics and higher proportion of CRAMS business (46%) were the key highlights of the quarter. Improvement in margins: led by higher overseas and CRAMS sales, a 5. 9% YoY depreciation in the Rupee v/s the USD and increased captive consumption from companies like Dishman, Lupin and Piramal Healthcare. Raw material pressure to persist in the near term: Chinaââ¬â¢s decision to (i) shut down polluting plants around Beijing and (ii) restrict the movement of hazardous chemicals in view of the Olympics resulted in raw material shortages and a consequent increase in prices. A rise in crude oil prices resulted in increases in the price of API solvents and intermediates. Our interaction with a few companies suggests that raw material shortage may persist for the next one-two quarters. Depreciating rupee leads to MTM losses on Forex debt: A 7. % and 9% QoQ depreciation of the rupee v/s the USD and Euro respectively resulted in most companies declaring MTM losses on their FCCBs and foreign debt. Prominent among the losers were Ranbaxy, Jubilant and Cipla. GSK recently signed a deal with Aspen and Strides GSK Pharmaceutical has collaborated with Aspen through which it would have access to a portfolio comprising 1200 products and 450 molecules of Aspen and its JV with Strides. GSK would get these products approved in 95 emerging markets and distribute and market these as well, while Aspen will continue to market in Sub-Saharan Africa and other countries. Jubilant signs drug discovery pact with Amgen Jubilant Bosys Ltd. and Amgen Inc. , the largest US-based biotech company on Monday announced a drug discovery partnership. As per the deal, Amgen and Jubilant will collaborate to develop a portfolio of novel drugs in new target areas of interest across multiple therapeutic areas. Jubilant will develop early preclinical candidates emanating from Amgens early discovery efforts for an initial term of three years. Amgen will have responsibility for the subsequent pre-clinical and clinical development and commercialization. Amgen will retain / own the drugs developed under the collaboration with worldwide commercialization rights. Jubilant Biosys will partner in early-preclinical development effort from its state of the art Jubilant Research Centre Bangalore, while Amgen will pursue later stage pre-clinical and clinical development and commercialization of the drugs in global markets. The financial terms include a combination of research funding and success-based milestones paid to Jubilant during pre-clinical and clinical development for multiple projects undertaken by the collaboration. The total financial Milestone value is subject to successful development and commercialization of the portfolio of novel drugs. Glenmark`s molecule for Neuropathetic Pain to enter Phase I trials Glenmark Pharmaceuticals Ltd has announced that its candidate for Neuropathic Pain, Osteoarthritis and other Inflammatory Pain-GRC 10693 is entering Phase I trials. The company intends to develop GRC 10693, a cannabinoid-2 (CB-2) receptor agonist, in neuropathic pain as the primary indication. The molecule has been filed for Phase-I approval with European regulatory authorities. Biocon, Abraxis launches ABRAXANE in India Biocon Limited and Abraxis BioScience, Inc, a fully integrated biotechnology company announced the launch of ABRAXANE (paclitaxel protein bound particles for injectable suspension) (albumin-bound) in India for the treatment of breast cancer after failure of combination therapy for metastatic disease or relapse within six months of adjuvant chemotherapy, ABRAXANE is now available in India as a single-use 100 mg vial (as a lyophilized powder, to be reconstituted for intravenous administration). The Phase III clinical trial in the U. S. demonstrated that ABRAXANE nearly doubled the response rate, significantly prolonged time to progression, and significantly improved overall survival in the secon line setting versus solvent based Taxol in the approved indication. The Medical House ties up with Dr Reddys Labs The Medical House Plc, a drug delivery specialist has signed a non-exclusive development, licensing and supply agreement with Dr Reddys Laboratories. The agreement covers an initial five-year term of supply, within US, European Union and Canada, with an option for Dr Reddys to extend the agreement to the rest of the world, on mutually agreed terms, the company said in a filing to the London Stock Exchange. The duration of the agreement can also be extended by mutual agreement and the development costs associated with customization would be paid to The Medical House (TMH) in addition to reimbursement of all agreed external costs. Strides completes acquisition of Ascent Pharmahealth Strides Arcolab has completed the acquisition of controlling interest in Ascent Pharmahealth Limited (formerly Genepharm Australasia Limited), thereby making Strides the 4th largest Generics Company in Australia. Strides now holds 50. 1% stake in Ascent Pharmahealth Limited, an ASX listed company. At final closing in Sept ââ¬â¢08, Strides may own upto 55% in Ascent Pharmahealth Ltd. Shareholders have voted to change the name of Genepharm Australasia Limited to Ascent Pharmahealth Limited. Ascent Pharmahealth Limited will include the assets of Drug Houses of Australia [DHA] in Singapore, a wholly owned subsidiary of Strides Revenue in excess of US$90mn on a combined Performa basis. Lupin acquires Hormosan Pharma Lupin Ltd has acquired Hormosan Pharma GmbH (Hormosan), a German Sales and Marketing generics company specialized in the supply of pharmaceutical products for the Central Nervous System (CNS). Hormosan, with total sales of Euro 6. 8mn for the year ended December 2007, develops, licenses and markets a range of generics in Germany. Hormosan has a complementary product portfolio with products in the Central Nervous System and Cardiovascular therapeutic segments. Hormosan has created a strong brand identity in the German generics market through its strong patient compliance message, essential for patients within the CNS sector. Besides strong key account management the company also has a successful in Regulatory team, Pharmacovigilance, Medical Information and Marketing teams. Aurobindo Pharma receives nod for 2 ANDAs Aurobindo Pharma has received final approval from the US Food Drug Administration (USFDA) for 2 ANDAs namely Ceftriaxone for injection USP 250mg, 500mg, 2g and Ceftriaxone for injection USP 10g pharmacy bulk pack. These are Cephalosporins under the Anti-infective segment. Lupin Pharma receives nod for Divaiproex. Sodium Tablets Lupin Pharmaceuticals, Inc. (LPI) has received final approval for the Companys Abbreviated New Drug Application (ANDA) for Divaiproex Sodium Delayed-Release Tablets, 125 mg, 250 mg and 500 mg from the U. S. Food and Drug Administration (USFDA). Commercial shipments of the product have already commenced. Lupin Divaiproex sodium delayed-release tablets are the AB-rated generic equivalent of Abbott Laboratories Depakote tablets. Depakote had annual sales of approximately US$ 803mn for the twelve months ended March 2008, based on IMS Health sales data. Dr Reddy`s lab to invest in Perlecan Pharma Dr Reddys lab has purchased holding of Citigroup Venture Capital International Mauritius Limited its nominees and IDBI Trusteeship Services Limited (the merged entity after its merger with The Western India Trustee and the Executor Company Limited) in Perlecan Pharma Private Limited. The Board of Directors of Dr Reddys Laboratories Limited at their meeting held on July 21, 2008 had approved this proposal aggregating to US$18mn. References: pharmaceutical-drug-manufacturers. com/pharmaceutical-industry/ thehindubusinessline. com/iw/2004/07/25/stories/2004072500401000. htm ibef. org/industry/pharmaceuticals. aspx www. indiainbusiness. nic. in/industry-infrastructure/industrial-sectors/drug-pharma. htm
Thursday, November 21, 2019
Interpersonal Conflict in Film Essay Example | Topics and Well Written Essays - 750 words
Interpersonal Conflict in Film - Essay Example tales being linked together, surprisingly, the director somehow manages to make the whole plot gel together to form an outstanding collage of significant chronicles and to convey a positive message for its audience. Crash is basically an analogy of the inter-racial conflict that exists in the American society. A crash or a collision by definition happens when there is a conflict in peopleââ¬â¢s individual beliefs and ideas. What makes Crash exceptional is that it is far from predictable ââ¬â ââ¬Å"we understand quickly enough who the characters are and what their lives are like, but we have no idea how they will behave, because so much depends on accidentâ⬠(Ebert, 2005). What is worth noting, however, is that there are actually several portions of the film where interpersonal conflict was not handled effectively. This paper will focus on only one of the more intense interpersonal conflicts depicted in this film. The character this essay will be focused on is Cameron Thayer, a role portrayed by Terrence Howard. Cameron is a director for a television program, and he and his wife, become the subject of a policemanââ¬â¢s acts of prejudice against blacks. While driving home one night from work, Cameronââ¬â¢s Navigator is pulled over by two police officers, and due to his wifeââ¬â¢s misconduct ââ¬â being drunk, behaving argumentatively and not following orders ââ¬â Christine (Cameronââ¬â¢s wife), is molested in front of him by LAPD officer John Ryan. Cameron does not do anything while she is being violated, and this act of not doing anything becomes the subject of the interpersonal conflict between Cameron and Christine. The conflict between the couple was unavoidable because at the time of the occurrence, Christine was drunk and acting impulsively. Before the molesting incident, Cameron tried to practice placating (Sole, 2011, p. 200) to avoid the situation from getting worse. She was uncontrollable, however, thus causing the way that the police officer treated her. This is not
Wednesday, November 20, 2019
One recent developments within transportation infrastructure that has Essay
One recent developments within transportation infrastructure that has contributed to increased efficiencies in transportation and distribution - Essay Example ver time, some urban areas have developed a framework aimed at creating a sustainable freight transport system and enhancing the sustainability of intermodal railroad transport. IRRT integrates modal shift strategies and urban freight. Therefore, it is vital that local authorities play a vital role to achieve the implementation of this framework. This framework can help to guide urban planners in overcoming urban transportââ¬â¢s existing shortcomings. This paper will also illustrate the benefits to local sustainability that intermodal railroad transport will bring. Producers within the supply chain are involved in movement of multiple goods, whether this involves the customer or the supplier (Vallespir, 2010: p101). Logistics, essentially, involves the flow of goods and materials along the chain of supply including all other activities that are related. Transportation is part of logistics and involves moving of goods and services from the point of creation to the point of consumption. This creates place and time utility because a product that is produced at one point is of very little value, to the potential customer unless available where the customer can access it. Therefore, freight transport is very important to public welfare generation. Distribution, on the other hand, can be referred to as moving the product from the stage of supply to the client stage in the chain of supply. Different networks of distribution exist such as direct shipping, retail storage, and distribution storage. Such parameters of production such as desired time of d elivery, product value, and demand determine the distribution network design to be used. This, in turn, determines the transport requirements. Freight transportââ¬â¢s implications include an increasing demand for shipping and delivery of goods in smaller units and a higher frequency, as well as speed and reliability. Urban freight transport consists of numerous interactions and interests. In order to achieve urban freight
Sunday, November 17, 2019
Rhetorical Precis Essay Example for Free
Rhetorical Precis Essay In The Organization Kid, an article published in The Atlantic Monthly in April of 2001, David Brooks discusses the willing conformism and social subservience of the educational elite and reinforces his points through usage of a heavily pathos-based timeline, quotes, textual examples and statistics. Brooksââ¬â¢ examples are both well structured and particularly effective. He compartmentalizes his arguments, shows instances of change over time and directly and effectively targets the emotions of his audience. Brooksââ¬â¢ masterful usage of tactics and strategies such as this makes the narrative quite effective in terms of emphasizing his main goal: drawing attention to the growing trend of willing subservience amongst the educational elite. Brooksââ¬â¢ statement is indeed quite relevant in reference to major issues in ever-changing modern society. Vocabulary * Prudential ââ¬â Involving or showing care and forethought, typically in business. * Sacrosanct ââ¬â Regarded as too important or valuable to be interfered with. * Meritocratic ââ¬â Government or the holding of power by people selected on the basis of their ability. * Nihilism ââ¬â The rejection of all religious and moral principals, often in the belief that life is meaningless. * Ganglia ââ¬â A structure containing a number of nerve cell bodies, typically linked by synapses, and often forming a swelling on a nerve fiber. Tone * Critical * Analytic * Factual * Condemnatory Rhetorical Strategies * Hyperbole ââ¬â ââ¬Å"soul crushingâ⬠* Asyndeton ââ¬â ââ¬Å"there are pesticides on our fruit, cigarettes in the school yards, rocks near the bike paths, kidnappers in the woods.â⬠* Alliteration ââ¬â ââ¬Å"Baby Boomersâ⬠* Personification ââ¬â ââ¬Å"the argument speaksâ⬠* Simile ââ¬â ââ¬Å"like flies to a lightâ⬠Discussion Questions * Clarification ââ¬â Why does the author draw different conclusions regarding societal issues at the end of the narrative than he at the beginning? * Style ââ¬â Does the writerââ¬â¢s style of citing sometimes-unrelated information to support his argument act as beneficial or detrimental in regards to emphasizing his points? * Application ââ¬â While the author certainly made his perceived issues with todayââ¬â¢s society quite clear, he never exactly expanded on what he would do to repair it. What do you believe would be the best course of action to take to restore the missing sense of the ââ¬Å"ultimate challengeâ⬠and ââ¬Å"ultimate rewardâ⬠? Important Quotation ââ¬Å"The most sophisticated people in preceding generations were formed by their struggle to break free from something. The most sophisticated people in this one arenââ¬â¢t.ââ¬
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